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Cheap flights Guayaquil to Panama City (Tocumen)

1 passenger, economy

Cheap flights Guayaquil to Panama City

Compare prices, duration and stops

Avianca
AV 76
20:45
Guayaquil (GYE)
Wed, 16 sep
8h 50min
1 stop
05:35
Panama City, Tocumen (PTY)
Thu, 17 sep +1
282 S$
Avianca
AV 8380
08:30
Guayaquil (GYE)
Thu, 17 sep
5h 45min
1 stop
14:15
Panama City, Tocumen (PTY)
Thu, 17 sep
217 S$
Avianca
AV 8380
08:30
Guayaquil (GYE)
Thu, 24 sep
10h 45min
1 stop
19:15
Panama City, Tocumen (PTY)
Thu, 24 sep
259 S$
Copa Air
CM 379
23:28
Guayaquil (GYE)
Thu, 24 sep
2h 12min
Direct
01:40
Panama City, Tocumen (PTY)
Fri, 25 sep +1
210 S$
Avianca
AV 8384
15:05
Guayaquil (GYE)
Sat, 26 sep
6h 55min
1 stop
22:00
Panama City, Tocumen (PTY)
Sat, 26 sep
259 S$
Copa Air
CM 377
17:18
Guayaquil (GYE)
Tue, 13 oct
2h 16min
Direct
19:34
Panama City, Tocumen (PTY)
Tue, 13 oct
262 S$
Avianca
AV 8380
08:30
Guayaquil (GYE)
Tue, 10 nov
5h 20min
1 stop
13:50
Panama City, Tocumen (PTY)
Tue, 10 nov
213 S$
Avianca
AV 8384 Best price
15:25
Guayaquil (GYE)
Wed, 11 nov
6h 30min
1 stop
21:55
Panama City, Tocumen (PTY)
Wed, 11 nov
202 S$
Avianca
AV 8384
15:10
Guayaquil (GYE)
Fri, 13 nov
7h 5min
1 stop
22:15
Panama City, Tocumen (PTY)
Fri, 13 nov
240 S$
Avianca
AV 8388
14:10
Guayaquil (GYE)
Tue, 17 nov
6h 5min
1 stop
20:15
Panama City, Tocumen (PTY)
Tue, 17 nov
219 S$
Avianca Ecuador
2K 8388
14:10
Guayaquil (GYE)
Thu, 17 dec
8h 5min
1 stop
22:15
Panama City, Tocumen (PTY)
Thu, 17 dec
260 S$
Copa Air
CM 379
23:34
Guayaquil (GYE)
Mon, 28 dec
2h 16min
Direct
01:50
Panama City, Tocumen (PTY)
Tue, 29 dec +1
271 S$
Copa Air
CM 377
17:22
Guayaquil (GYE)
Tue, 29 dec
2h 17min
Direct
19:39
Panama City, Tocumen (PTY)
Tue, 29 dec
271 S$
Avianca Ecuador
2K 8380
08:30
Guayaquil (GYE)
Wed, 13 jan
5h 40min
1 stop
14:10
Panama City, Tocumen (PTY)
Wed, 13 jan
227 S$
Avianca Ecuador
2K 8380
08:30
Guayaquil (GYE)
Thu, 14 jan
5h 40min
1 stop
14:10
Panama City, Tocumen (PTY)
Thu, 14 jan
225 S$
Avianca Ecuador
2K 8388
14:10
Guayaquil (GYE)
Thu, 14 jan
6h 5min
1 stop
20:15
Panama City, Tocumen (PTY)
Thu, 14 jan
223 S$
Avianca Ecuador
2K 8394
00:35
Guayaquil (GYE)
Mon, 8 mar
13h 35min
1 stop
14:10
Panama City, Tocumen (PTY)
Mon, 8 mar
238 S$
Copa Air
CM 214
06:59
Guayaquil (GYE)
Sat, 10 July
2h 11min
Direct
09:10
Panama City, Tocumen (PTY)
Sat, 10 July
304 S$

Low price calendar

September 2026
Price chart (September 2026)
min: 210 S$ · max: 282 S$
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210 S$
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Cheap flights Guayaquil to Panama City

Avianca
Avianca
Tue, Wed, Thu, Fri, Sat
Price from
S$202
Copa Air
Copa Air
Mon, Tue, Thu, Sat
Price from
S$210

Popular destinations from Guayaquil

All →
GYE
Guayaquil — Quito
Ecuador → Ecuador
UIO
from
S$91
GYE
Guayaquil — Cuenca
Ecuador → Ecuador
CUE
from
S$95
GYE
Guayaquil — Galapagos Islands
Ecuador → Ecuador
GPS
from
S$164
GYE
Guayaquil — San Cristobal
Ecuador → Ecuador
SCY
from
S$175
GYE
Guayaquil — Santiago
Ecuador → Chile
SCL
from
S$231
GYE
Guayaquil — New York
Ecuador → United States
NYC
from
S$235
GYE
Guayaquil — Coca
Ecuador → Ecuador
OCC
from
S$245
GYE
Guayaquil — Cali
Ecuador → Colombia
CLO
from
S$262

Popular destinations to Panama City

All →
DAV
David — Panama City
Panama → Panama
PTY
from
S$81
BOC
Bocas Del Toro — Panama City
Panama → Panama
PTY
from
S$82
SJO
San Jose — Panama City
Costa Rica → Panama
PTY
from
S$116
SAL
San Salvador — Panama City
El Salvador → Panama
PTY
from
S$163
BOG
Bogota — Panama City
Colombia → Panama
PTY
from
S$167
UIO
Quito — Panama City
Ecuador → Panama
PTY
from
S$180
TPA
Tampa — Panama City
United States → Panama
PTY
from
S$189
MEX
Mexico City — Panama City
Mexico → Panama
PTY
from
S$200
GUA
Guatemala City — Panama City
Guatemala → Panama
PTY
from
S$206

Cheap flights Guayaquil to Panama City

Interesting facts about the route

Flight time

6h 5min

Distance

1 247 km

Average price

S$240

Most frequent flight

AV 8380

Passenger reviews

No reviews for this route yet

Internet abroad

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All plans

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15

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S$19

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2 GB

data

15

days

S$22

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3 GB

data

30

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3 GB

data

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S$29

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Frequently Asked Questions

The average ticket price Guayaquil Panama City is S$240. The cheapest ticket costs S$217, operated by Avianca, flight 8380, departing Guayaquil on 17 September at 08:30, arriving Panama City on 17 September at 14:15.
The average flight time is 8 hours 50 minutes. The fastest flight takes 5 hours 45 minutes, flight 8380 operated by Avianca, departing Guayaquil on 17 September at 08:30, arriving Panama City on 17 September at 14:15.
Flights on the Guayaquil - Panama City route are operated by the following airlines: Avianca, Copa Air.
The distance from Guayaquil to Panama City is 1247 km.