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Cheap flights Guayaquil to Santiago (Arturo Merino Benitez)

1 passenger, economy

Cheap flights Guayaquil to Santiago

Compare prices, duration and stops

Avianca
AV 8388
14:10
Guayaquil (GYE)
Thu, 17 sep
13h 10min
1 stop
03:20
Santiago, Arturo Merino Benitez (SCL)
Fri, 18 sep +1
273 $
LATAM Chile
LA 1430
14:00
Guayaquil (GYE)
Fri, 18 sep
11h 55min
1 stop
01:55
Santiago, Arturo Merino Benitez (SCL)
Sat, 19 sep +1
277 $
LATAM Chile
LA 1447
22:38
Guayaquil (GYE)
Wed, 23 sep
4h 51min
Direct
03:29
Santiago, Arturo Merino Benitez (SCL)
Thu, 24 sep +1
264 $
LATAM Chile
LA 1430
14:00
Guayaquil (GYE)
Thu, 24 sep
6h 45min
1 stop
20:45
Santiago, Arturo Merino Benitez (SCL)
Thu, 24 sep
269 $
Avianca Ecuador
2K 8384
15:05
Guayaquil (GYE)
Fri, 25 sep
12h 15min
1 stop
03:20
Santiago, Arturo Merino Benitez (SCL)
Sat, 26 sep +1
295 $
Copa Air
CM 379
23:28
Guayaquil (GYE)
Sun, 27 sep
27h 54min
1 stop
03:22
Santiago, Arturo Merino Benitez (SCL)
Tue, 29 sep +1
279 $
LATAM Chile
LA 1430 Best price
14:05
Guayaquil (GYE)
Tue, 17 nov
6h 55min
1 stop
21:00
Santiago, Arturo Merino Benitez (SCL)
Tue, 17 nov
193 $
LATAM Chile
LA 1430
14:05
Guayaquil (GYE)
Tue, 1 dec
10h 45min
1 stop
00:50
Santiago, Arturo Merino Benitez (SCL)
Wed, 2 dec +1
206 $
Avianca Ecuador
2K 8380
08:30
Guayaquil (GYE)
Wed, 6 jan
9h 40min
1 stop
18:10
Santiago, Arturo Merino Benitez (SCL)
Wed, 6 jan
219 $
LATAM Chile
LA 1448
01:45
Guayaquil (GYE)
Fri, 9 apr
7h 5min
1 stop
08:50
Santiago, Arturo Merino Benitez (SCL)
Fri, 9 apr
265 $

Low price calendar

September 2026
Price chart (September 2026)
min: 264 $ · max: 295 $
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Cheap flights Guayaquil to Santiago

LATAM Chile
LATAM Chile
Tue, Wed, Thu, Fri
Price from
$193
Avianca
Avianca
Thu
Price from
$273
Copa Air
Copa Air
Sun
Price from
$279
Avianca Ecuador
Avianca Ecuador
Wed, Fri
Price from
$295

Popular destinations from Guayaquil

All →
GYE
Guayaquil — Quito
Ecuador → Ecuador
UIO
from
$72
GYE
Guayaquil — Cuenca
Ecuador → Ecuador
CUE
from
$75
GYE
Guayaquil — Galapagos Islands
Ecuador → Ecuador
GPS
from
$129
GYE
Guayaquil — San Cristobal
Ecuador → Ecuador
SCY
from
$137
GYE
Guayaquil — Panama City
Ecuador → Panama
PTY
from
$170
GYE
Guayaquil — New York
Ecuador → United States
NYC
from
$184
GYE
Guayaquil — Coca
Ecuador → Ecuador
OCC
from
$192
GYE
Guayaquil — Cali
Ecuador → Colombia
CLO
from
$206

Popular destinations to Santiago

All →
CJC
Calama — Santiago
Chile → Chile
SCL
from
$10
LSC
La Serena — Santiago
Chile → Chile
SCL
from
$19
ANF
Antofagasta — Santiago
Chile → Chile
SCL
from
$23
ZCO
Temuco — Santiago
Chile → Chile
SCL
from
$24
CCP
Concepcion — Santiago
Chile → Chile
SCL
from
$24
PMC
Puerto Montt — Santiago
Chile → Chile
SCL
from
$24
CPO
Copiapo — Santiago
Chile → Chile
SCL
from
$25
IQQ
Iquique — Santiago
Chile → Chile
SCL
from
$29
ARI
Arica — Santiago
Chile → Chile
SCL
from
$40

Cheap flights Guayaquil to Santiago

Interesting facts about the route

Flight time

9h 40min

Distance

3 601 km

Average price

$265

Most frequent flight

LA 1430

Passenger reviews

No reviews for this route yet

Internet abroad

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All plans

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3 GB

data

30

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5 GB

data

30

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$16

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10 GB

data

30

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$28

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20 GB

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30

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$48

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altoque

1 GB

data

7

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$5

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Frequently Asked Questions

The average ticket price Guayaquil Santiago is $265. The cheapest ticket costs $273, operated by Avianca, flight 8388, departing Guayaquil on 17 September at 14:10, arriving Santiago on 18 September at 03:20.
The average flight time is 13 hours 10 minutes. The fastest flight takes 11 hours 55 minutes, flight 1430 operated by LATAM Chile, departing Guayaquil on 18 September at 14:00, arriving Santiago on 19 September at 01:55.
Flights on the Guayaquil - Santiago route are operated by the following airlines: Avianca Ecuador, Avianca, Copa Air, LATAM Chile.
The distance from Guayaquil to Santiago is 3601 km.