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Cheap flights Madrid (Adolfo Suarez Madrid-Barajas) to Guarulhos - Governador André Franco Montoro International Airport

1 passenger, economy

Nonstop flights from Madrid to Guarulhos - Governador André Franco Montoro International Airport: Iberia, LATAM Chile, LATAM Brasil and 1 more. Nonstop flights per week: 28. Flight time: 11 hours 10 minutes. Distance: 8375 km. Tickets from KSh39 623 (departure 18 March).

Prices updated on 12 November at 11:13

See also: Flights from Madrid (Adolfo Suarez Madrid-Barajas)Flights to Guarulhos - Governador André Franco Montoro International Airport (Sao Paulo)

Cheap flights Madrid to Guarulhos - Governador André Franco Montoro International Airport

Compare prices, duration and stops

TAP Portugal
TP 1011
10:20
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
17h 35min
1 stop
23:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 12 Nov
KSh63 786
United Airlines
UA 261
11:00
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
27h 20min
1 stop
10:20
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov +1
KSh66 348
TAP Portugal
TP 1013
14:10
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
15h 45min
1 stop
01:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov +1
KSh60 887
Royal Air Maroc
AT 973
15:00
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
13h 25min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov +1
KSh68 042
TAP Portugal
TP 1015
14:55
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
18h 45min
2 stops
05:40
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov +1
KSh70 097
ITA Airways
AZ 63
18:00
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 12 Nov
28h 40min
1 stop
18:40
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov +1
KSh65 406
Air Europa
UX 57
01:55
Adolfo Suarez Madrid-Barajas (MAD)
Fri, 13 Nov
10h 35min
Direct
08:30
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov
KSh67 425
ITA Airways
AZ 59
05:55
Adolfo Suarez Madrid-Barajas (MAD)
Fri, 13 Nov
16h 45min
1 stop
18:40
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov
KSh63 098
Portugália
NI 1011
12:20
Adolfo Suarez Madrid-Barajas (MAD)
Fri, 13 Nov
13h 35min
1 stop
21:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 13 Nov
KSh62 376
Air Europa
UX 1145
10:35
Adolfo Suarez Madrid-Barajas (MAD)
Fri, 13 Nov
37h 20min
2 stops
19:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sat, 14 Nov +1
KSh72 318
Royal Air Maroc
AT 971
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Fri, 13 Nov
31h 20min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh75 565
Air Europa
UX 1159
06:30
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
31h 25min
2 stops
09:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh75 435
Avianca
AV 27
10:10
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
18h 45min
1 stop
00:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh72 068
TAP Portugal
TP 1011
10:20
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
27h 25min
2 stops
09:45
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh67 926
EasyJet Europe
EC 7640
10:30
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
31h 15min
2 stops
13:45
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh58 403
Easyjet
U2 7640
10:30
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
61h 25min
1 stop
19:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov +1
KSh68 733
Royal Air Maroc
AT 973
15:00
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
13h 25min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh74 445
TAP Portugal
TP 1017
20:00
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
33h 55min
1 stop
01:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov +1
KSh63 169
ITA Airways
AZ 63
18:00
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
28h 40min
1 stop
18:40
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov +1
KSh64 553
Air Europa
UX 1141
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
52h 50min
2 stops
21:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov +1
KSh65 931
Portugália
NI 1021
21:10
Adolfo Suarez Madrid-Barajas (MAD)
Sat, 14 Nov
36h 40min
3 stops
05:50
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov +1
KSh78 528
Air Europa
UX 57
01:55
Adolfo Suarez Madrid-Barajas (MAD)
Sun, 15 Nov
10h 35min
Direct
08:30
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Sun, 15 Nov
KSh67 372
Ryanair
FR 572
11:15
Adolfo Suarez Madrid-Barajas (MAD)
Sun, 15 Nov
62h 45min
1 stop
22:00
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh69 236
Royal Air Maroc
AT 971
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Sun, 15 Nov
31h 20min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh71 077
Portugália
NI 1021
21:10
Adolfo Suarez Madrid-Barajas (MAD)
Sun, 15 Nov
52h 50min
2 stops
22:00
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh66 498
Air Europa
UX 57
23:55
Adolfo Suarez Madrid-Barajas (MAD)
Sun, 15 Nov
10h 35min
Direct
06:30
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov +1
KSh64 840
TAP Portugal
TP 1023
09:40
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
20h 15min
1 stop
01:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh60 520
EuroAtlantic Airways
YU 8001
10:25
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
17h 25min
1 stop
23:50
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Mon, 16 Nov
KSh66 135
United Airlines
UA 261
11:00
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
27h 20min
1 stop
10:20
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh72 738
Royal Air Maroc
AT 973
15:00
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
13h 25min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh63 804
Ryanair
FR 572
14:05
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
35h 55min
1 stop
22:00
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh64 524
ITA Airways
AZ 63
18:00
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
28h 40min
1 stop
18:40
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh64 486
Royal Air Maroc
AT 971
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
31h 20min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Wed, 18 Nov +1
KSh69 619
Portugália
NI 1021
21:10
Adolfo Suarez Madrid-Barajas (MAD)
Mon, 16 Nov
28h 50min
2 stops
22:00
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov +1
KSh61 425
Air Europa
UX 57
01:55
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
10h 35min
Direct
08:30
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov
KSh76 038
TAP Portugal
TP 1023
07:40
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
18h 20min
2 stops
22:00
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Tue, 17 Nov
KSh61 642
Royal Air Maroc
AT 973
15:00
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
13h 25min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Wed, 18 Nov +1
KSh68 595
ITA Airways
AZ 63
18:00
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
16h 25min
1 stop
06:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Wed, 18 Nov +1
KSh62 916
Royal Air Maroc
AT 971
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
31h 20min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh72 285
Portugália
NI 1021
21:10
Adolfo Suarez Madrid-Barajas (MAD)
Tue, 17 Nov
52h 55min
2 stops
22:05
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh62 648
Easyjet
U2 7640
09:50
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
34h 5min
1 stop
15:55
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh57 897
TAP Portugal
TP 1011
10:20
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
39h 45min
2 stops
22:05
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh61 439
ITA Airways
AZ 61
11:40
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
22h 45min
1 stop
06:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh62 499
Royal Air Maroc
AT 973
15:00
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
13h 25min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh71 112
TAP Portugal
TP 1015 🔥 Hot deal
14:55
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
35h 10min
2 stops
22:05
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh60 985
ITA Airways
AZ 63
18:00
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
16h 25min
1 stop
06:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh63 795
Royal Air Maroc
AT 971
21:05
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
31h 20min
1 stop
00:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 20 Nov +1
KSh70 517
TAP Portugal
TP 1021
21:10
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
28h 55min
2 stops
22:05
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh61 150
Air Europa
UX 57
23:55
Adolfo Suarez Madrid-Barajas (MAD)
Wed, 18 Nov
10h 35min
Direct
06:30
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Thu, 19 Nov +1
KSh66 519
ITA Airways
AZ 59
05:55
Adolfo Suarez Madrid-Barajas (MAD)
Thu, 19 Nov
28h 30min
1 stop
06:25
Guarulhos - Governador André Franco Montoro International Airport (GRU)
Fri, 20 Nov +1
KSh63 736

Direct flight schedule Madrid — Guarulhos - Governador André Franco Montoro International Airport

Direct flights: 6 · Airlines: 4 · First departure: 01:55 · Last departure: 23:55

Departure → arrivalFlightAirport DaysDurationPrice
01:55→08:30 Air Europa UX 57 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 10h 35min
11:50→19:00 Iberia IB 271 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 11h 10min
13:50→20:25 LATAM Brasil JJ 8075 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 10h 35min
13:50→19:35 LATAM Chile LA 8075 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 10h 45min
22:45→04:20+1 LATAM Chile LA 8065 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 10h 35min
23:55→07:05+1 Iberia IB 267 Adolfo Suarez Madrid-BarajasMAD MonTueWedThuFriSatSun 11h 10min
Local time: departure at the departure airport, arrival at the arrival airport. Days and prices are based on tickets found for the coming months.

Low price calendar

From
To
Lowest price of the month Sat, 14 Nov · One way from KSh58 403

Prices as of 12 November, 11:15 Moscow time

Cheap flights Madrid to Guarulhos - Governador André Franco Montoro International Airport

Avianca
Avianca
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh39 623
Iberia
Iberia
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh50 354
LATAM Chile
LATAM Chile
Mon, Tue, Wed, Fri, Sat
Price from
KSh52 084
Ryanair
Ryanair
Mon, Thu, Fri, Sat, Sun
Price from
KSh53 915
Latam Airlines Peru
Latam Airlines Peru
Thu
Price from
KSh54 717
LATAM Brasil
LATAM Brasil
Sat
Price from
KSh55 327
Easyjet
Easyjet
Mon, Tue, Wed, Sat, Sun
Price from
KSh55 667
EasyJet Europe
EasyJet Europe
Mon, Thu, Sat
Price from
KSh58 403
ITA Airways
ITA Airways
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh58 487
Royal Air Maroc
Royal Air Maroc
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh58 519
TAP Portugal
TAP Portugal
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh59 556
EuroAtlantic Airways
EuroAtlantic Airways
Mon, Wed, Fri
Price from
KSh60 158
Portugália
Portugália
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh62 648
United Airlines
United Airlines
Mon, Tue, Thu, Fri
Price from
KSh66 348
Air Europa
Air Europa
Mon, Tue, Wed, Thu, Fri, Sat, Sun
Price from
KSh70 258

Which airlines offer the cheapest flights from Madrid to Guarulhos - Governador André Franco Montoro International Airport?

Based on collected data, the cheapest flights are offered by Latam Airlines Peru with an average ticket price of KSh54 717.

  • Latam Airlines Peru Average price: KSh54 717 · Flights: 1 · Direct: 0
  • LATAM Brasil Average price: KSh54 853 · Flights: 1 · Direct: 1
  • Iberia Average price: KSh56 823 · Flights: 5 · Direct: 2
  • LATAM Chile Average price: KSh57 887 · Flights: 4 · Direct: 2
  • EasyJet Europe Average price: KSh60 635 · Flights: 1 · Direct: 0
  • TAP Portugal Average price: KSh61 796 · Flights: 6 · Direct: 0
  • ITA Airways Average price: KSh64 055 · Flights: 6 · Direct: 0
  • Portugália Average price: KSh64 430 · Flights: 4 · Direct: 0
  • Royal Air Maroc Average price: KSh65 521 · Flights: 3 · Direct: 0
  • Azul Brazilian Airlines Average price: KSh65 550 · Flights: 2 · Direct: 0

Which airlines fly most often from Madrid to Guarulhos - Governador André Franco Montoro International Airport?

The most flight options on this route are offered by Air Europa — options found: 7.

  • Air Europa Flights: 7 · Direct: 1
  • TAP Portugal Flights: 6 · Direct: 0
  • ITA Airways Flights: 6 · Direct: 0
  • Avianca Flights: 6 · Direct: 0
  • Iberia Flights: 5 · Direct: 2
  • LATAM Chile Flights: 4 · Direct: 2
  • Portugália Flights: 4 · Direct: 0
  • Royal Air Maroc Flights: 3 · Direct: 0
  • Ryanair Flights: 3 · Direct: 0
  • Easyjet Flights: 3 · Direct: 0

Round trip Madrid — Guarulhos - Governador André Franco Montoro International Airport

TripOutboundReturnOutbound + returnTotal
Weekend tripSat, 5 DecSun, 6 Dec KSh46 603 + KSh39 907
One weekThu, 3 DecWed, 9 Dec KSh39 382 + KSh42 592
Two weeksTue, 17 NovTue, 1 Dec KSh58 415 + KSh34 676

Two one-way tickets combined, price per adult. Tap a price to search these dates.

Prices as of 12 November, 11:15 Moscow time

Which month is cheapest to fly Madrid — Guarulhos - Governador André Franco Montoro International Airport?

Cheapest month: March — a one-way ticket usually costs around KSh52 999, 14% below average. Most expensive month: May — around KSh66 111.

March 2027usually KSh52 999 · 14% below average

One-way ticket prices for departures in that month. “Usually” is the median of the lowest daily prices.

Prices as of 12 November, 11:15 Moscow time

How many days before departure is it cheapest to buy a Madrid — Guarulhos - Governador André Franco Montoro International Airport ticket?

The cheapest departure right now is Sat, 14 Nov — from KSh58 403. Days before departure: 2.

Before departureDeparture dateDifference from lowestPrice
1–3 days Sat, 14 Nov cheapest
4–7 days Wed, 18 Nov 5% more
8–14 days Fri, 20 Nov 1% more
15–21 days Mon, 30 Nov 2% more
22–30 days Sun, 6 Dec 10% more

Lowest prices for departures in the next 30 days.

How many flights per day operate from Madrid to Guarulhos - Governador André Franco Montoro International Airport?

Most flights operate on Mon (31), the fewest on Sun (18).

  • Mon Flights: 31 · Direct: 4
  • Tue Flights: 27 · Direct: 4
  • Wed Flights: 24 · Direct: 3
  • Thu Flights: 30 · Direct: 3
  • Fri Flights: 29 · Direct: 5
  • Sat Flights: 31 · Direct: 6
  • Sun Flights: 18 · Direct: 3

Popular destinations from Madrid

All →
MAD
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LON
from
KSh2 135
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Madrid — Rabat
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RBA
from
KSh2 141
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Madrid — Marrakech
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RAK
from
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TNG
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OPO
from
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MIL
from
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Popular destinations to Guarulhos - Governador André Franco Montoro International Airport

All →
FLN
Florianopolis — Sao Paulo
Brazil → Brazil
GRU
from
KSh4 385
RIO
Rio de Janeiro — Sao Paulo
Brazil → Brazil
GRU
from
KSh5 665
BHZ
Belo Horizonte — Sao Paulo
Brazil → Brazil
GRU
from
KSh6 580
JPA
Joao Pessoa — Sao Paulo
Brazil → Brazil
GRU
from
KSh10 266
SSA
Salvador — Sao Paulo
Brazil → Brazil
GRU
from
KSh11 059
REC
Recife — Sao Paulo
Brazil → Brazil
GRU
from
KSh11 620
IGU
Foz do Iguaçu — Sao Paulo
Brazil → Brazil
GRU
from
KSh11 770
SCL
Santiago — Sao Paulo
Chile → Brazil
GRU
from
KSh15 152
LIM
Lima — Sao Paulo
Peru → Brazil
GRU
from
KSh18 497

Cheap flights Madrid to Guarulhos - Governador André Franco Montoro International Airport

Price from
KSh39 623
Average price
KSh64 183
Cheapest
March
Flight time
11 hours 10 minutes
Distance
8 375 km
Рейсов в неделю
28
Airlines
17
Most frequent flight
AT 971

Prices as of 12 November, 11:13 Moscow time

Airports on the Madrid — Guarulhos - Governador André Franco Montoro International Airport route

From → to Flights Direct Airlines Price from
Adolfo Suarez Madrid-BarajasMAD Guarulhos - Governador André Franco Montoro International AirportGRU
59617

Departure airports · Madrid

Arrival airports · Guarulhos - Governador André Franco Montoro International Airport

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KSh1 758

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Frequently Asked Questions

Yes. Nonstop flights from Madrid to Guarulhos - Governador André Franco Montoro International Airport are operated by: Iberia, LATAM Chile, LATAM Brasil, Air Europa. A nonstop flight takes 11 hours 10 minutes on average. Nonstop tickets start at KSh47 838.
The average ticket price Madrid Guarulhos - Governador André Franco Montoro International Airport is KSh64 183. The cheapest ticket costs KSh39 623, operated by Avianca, flight AV 183, departing Madrid on 18 March at 10:10, arriving Guarulhos - Governador André Franco Montoro International Airport on 19 March at 01:15. Prices as of 12 November.
A nonstop flight takes 11 hours 10 minutes on average. The fastest is LA 8075 LATAM Chile: 10 hours 35 minutes. With a connection: from 13 hours 25 minutes, usually about 22 hours.
Based on prices for the coming months, the cheapest month to fly is March 2027: tickets from KSh39 623. The most expensive month is December, with tickets from KSh63 209.
Tickets from Madrid to Guarulhos - Governador André Franco Montoro International Airport are sold by: Air Europa, Avianca, ITA Airways, TAP Portugal, Iberia, LATAM Chile, Portugália, Royal Air Maroc, Ryanair, Easyjet. Nonstop: Iberia, LATAM Chile, LATAM Brasil, Air Europa.
The distance from Madrid to Guarulhos - Governador André Franco Montoro International Airport is 8375 km.
The first nonstop flight departs at 01:55 (UX 57, Air Europa), the last one at 23:55 (IB 267, Iberia). Local time.
Yes, the time difference is 4 hours: Madrid — UTC+1, Guarulhos - Governador André Franco Montoro International Airport — UTC−3. For example: Madrid 12:00 → Guarulhos - Governador André Franco Montoro International Airport 08:00.